Heartgard Plus (invermectin/pyrantel) is a veterinary medication used in the management of parasites. Specifically, Heartgard Plus (invermectin/pyrantel) fights heartworms, ascarids, and hookworms. There are Heartgard Plus (invermectin/pyrantel) tablets for dogs with dosages based on weight, as well as formulations specifically designed for use in cats. Heartgard Plus (invermectin/pyrantel) will not rid an animal of adult heartworms, but instead kills larval heartworms. If an animal is infected with adult heartworms, treatments to eradicate the adult parasites must be completed prior to beginning a course of Heartgard Plus (invermectin/pyrantel.) Test to determine if animal is infected with adult heartworm parasites is also required before starting on Heartgard Plus (invermectin/pyrantel.)
Heartgard Plus (invermectin/pyrantel) works by affecting the nervous systems of larval heartworms. By interfering with nerve transmissions, Heartgard Plus (invermectin/pyrantel) causes paralysis of the parasites, which allows the animal to pass the larva. Eventually, larvas die because of exposure to external elements, since they cannot survive outside the host. Doses must be administered every 30 days to ensure continued protection from heartworms and other parasites. If a dose is missed for more than 14 days, screening for adult heartworms must be completed before restarting Heartgard Plus (invermectin/pyrantel) to ensure no larva matured during the lapse in treatments.
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